Open AccessSaccharomyces cerevisiaeEssential Genes with an Opi− Phenotype
Author(s) -
Bryan Salas-Santiago,
John M. Lopes
Publication year - 2014
Publication title -
g3 genes genomes genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.468
H-Index - 66
ISSN - 2160-1836
DOI - 10.1534/g3.113.010140
Subject(s) - phenotype , saccharomyces cerevisiae , yeast , gene , overproduction , phospholipid , secretion , inositol , biology , genetics , microbiology and biotechnology , computational biology , biochemistry , receptor , membrane
The overproduction and secretion of inositol (i.e., Opi(-)) phenotype is associated with defects in regulation of phospholipid biosynthesis in yeast. Here we report a screen of the essential yeast gene set using a conditional-expression library. This screen identified novel functions previously unknown to affect phospholipid synthesis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom