REPORT ON FERTILITY AFTER VIRILIZATION WITH ANDROGENS IN A MAN WITH MINUTE TESTICLES AND EUNUCHOIDISM | Zendy

G. L. Foss | Zendy

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REPORT ON FERTILITY AFTER VIRILIZATION WITH ANDROGENS IN A MAN WITH MINUTE TESTICLES AND EUNUCHOIDISM

Author(s) -

G. L. Foss

Publication year - 1964

Publication title -

reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.208

H-Index - 136

eISSN - 1741-7899

pISSN - 1470-1626

DOI - 10.1530/jrf.0.0070373

Subject(s) - virilization , fertility , sertoli cell , spermatogenesis , andrology , testosterone (patch) , karyotype , medicine , androgen , gynecology , endocrinology , biology , physiology , hormone , chromosome , genetics , population , environmental health , gene

The case of a male eunuchoid aged 32 years is described. Of 46 XY karyotype, his testes showed complete absence of spermatogenesis. Small immature hyalinized tubules were lined only with Sertoli cells, and Leydig cells were difficult to find. After treatment for 8 years with androgens, at first by injection and for the rest of the time by mouth, he developed full virilization and later fertility. His wife became pregnant and gave birth to a child with cyanotic congenital heart disease.

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