Open AccessTen-year GH replacement increases bone mineral density in hypopituitary patients with adult onset GH deficiency
Author(s) -
G. Götherström,
B-Å Bengtsson,
Ingvar Bosæus,
Gudmundur Johannsson,
Johan Svensson
Publication year - 2007
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.02317
Subject(s) - medicine , endocrinology , bone mineral , femoral neck , hormone replacement therapy (female to male) , hypopituitarism , bone density , bone remodeling , growth hormone deficiency , estrogen , osteoporosis , growth hormone , hormone , testosterone (patch)
There are few studies that have determined the effects of long-term GH replacement on bone mineral density (BMD) in GH-deficient (GHD) adults. In this study, the effects of 10 years of GH replacement on BMD were assessed in 87 GHD adults using dual energy X-ray absorptiometry (DEXA). The results show that GH replacement induced a sustained increase in BMD at all the skeletal sites measured.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom