Open AccessTreatment of gonadotropin-deficient boys with recombinant human FSH: long-term observation and outcome
Author(s) -
Taneli Raivio,
Anne M. Wikström,
Leo Dunkel
Publication year - 2007
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.02315
Subject(s) - medicine , endocrinology , hypogonadotropic hypogonadism , spermatogenesis , hypogonadotrophic hypogonadism , gonadotropin , delayed puberty , follicle stimulating hormone , hormone , luteinizing hormone
Boys with prepubertal onset of hypogonadotropic hypogonadism (HH) are at a risk of poor testis growth and impaired spermatogenesis. One potential cause for this is deficient proliferation of immature Sertoli cells before and during puberty due to the absence of FSH.
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