Metabolic decompensation in children with type 1 diabetes mellitus associated with increased serum levels of the soluble leptin receptor | Zendy

Jürgen Kratzsch | Zendy; Ina Knerr | Zendy; Angela Galler | Zendy; Thomas Kapellen | Zendy; Klemens Raile | Zendy; Antje Körner | Zendy; Joachim Thiery | Zendy; Jörg Dötsch | Zendy; Wieland Kieß | Zendy

Open Access

Metabolic decompensation in children with type 1 diabetes mellitus associated with increased serum levels of the soluble leptin receptor

Author(s) -

Jürgen Kratzsch,

Ina Knerr,

Angela Galler,

Thomas Kapellen,

Klemens Raile,

Antje Körner,

Joachim Thiery,

Jörg Dötsch,

Wieland Kieß

Publication year - 2006

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.1.02261

Subject(s) - medicine , leptin , endocrinology , decompensation , insulin , type 1 diabetes , leptin receptor , diabetes mellitus , ketoacidosis , obesity

Type 1 diabetes mellitus (T1DM) leads to increased serum levels of the soluble leptin receptor (sOB-R) by an as yet unknown cellular mechanism. The aim of our study was to investigate potential metabolic factors that may be associated with the induction of the sOB-R release from its membrane receptor.

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