Changes in interleukin-6 and IGF system and their relationships in placenta and cord blood in newborns with fetal growth restriction compared with controls
Author(s) -
Maria Elisabeth Street,
Pietro Seghini,
Stefania Fieni,
Maria Angela Ziveri,
C. Volta,
Davide Martorana,
Isabella Viani,
Dandolo Gramellini,
Sergio Bernasconi
Publication year - 2006
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.02251
Subject(s) - placenta , cord blood , endocrinology , medicine , fetus , biology , gestation , messenger rna , cord , andrology , pregnancy , gene , biochemistry , genetics , surgery
The IGF system is central to fetal growth. Recently, the relationships between cytokines and the IGF system have been shown in specific tissues. It is unknown whether these occur in the placenta. The aim of this study was to assess whether interleukin-6 (IL-6) modulated the IGF system.
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