Open AccessThe effects of sex-steroid administration on the pituitary–thyroid axis in transsexuals
Author(s) -
Peter H. Bisschop,
Arno W. F. T. Toorians,
Erik Endert,
Wilmar M. Wiersinga,
Louis Gooren,
Eric Fliers
Publication year - 2006
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.02192
Subject(s) - medicine , endocrinology , testosterone (patch) , triiodothyronine , euthyroid , estrogen , cyproterone acetate , hormone , androgen , sex hormone binding globulin
Estrogen and androgen administration modulate the pituitary-thyroid axis through alterations in thyroid hormone-binding globulin (TBG) metabolism, but the effects of sex steroids on extrathyroidal thyroxine (T4) to triiodothyronine (T3) conversion in humans are unknown.
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