Effects of the long-acting somatostatin analogue Lanreotide Autogel on glucose tolerance and insulin resistance in acromegaly | Zendy

B Steffin | Zendy; B Gutt | Zendy; Martin Bidlingmaier | Zendy; C. Dieterle | Zendy; F Oltmann | Zendy; Jochen Schopohl | Zendy

Open Access

Effects of the long-acting somatostatin analogue Lanreotide Autogel on glucose tolerance and insulin resistance in acromegaly

Author(s) -

B Steffin,

B Gutt,

Martin Bidlingmaier,

C. Dieterle,

F Oltmann,

Jochen Schopohl

Publication year - 2006

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.1.02185

Subject(s) - acromegaly , medicine , endocrinology , somatostatin , insulin resistance , lanreotide , insulin , growth hormone , hormone

Treatment with somatostatin analogues (SA) not only inhibits GH secretion but may also impair insulin secretion. In order to evaluate the influence of SA on glucose metabolism, we investigated insulin resistance (IR) and beta-cell function, using the recommended combination of homeostatic model assessment of IR (HOMA-IR) and beta-cell function (HOMA-beta).

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