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To characterize the phenotype of a large population of Italian patients with adult onset (&gt; or =40 years) diabetes who were attending outpatient clinics and who were screened for glutamic acid decarboxylase 65 autoantibodies (GADA), protein tyrosine phosphatase IA-2 (IA-2A) and IA-2beta/phogrin (IA-2betaA).

Clinical phenotype and β-cell autoimmunity in Italian patients with adult-onset diabetes