Aromatase is differentially expressed in peripheral blood leukocytes from children, and adult female and male subjects | Zendy

Alessandra Vottero | Zendy; Vincenzo Rochira | Zendy; Marzia Capelletti | Zendy; Isabella Viani | Zendy; Lucia Zirilli | Zendy; Tauro Maria Neri | Zendy; Cesare Carani | Zendy; Sergio Bernasconi | Zendy; Lucia Ghizzoni | Zendy

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Aromatase is differentially expressed in peripheral blood leukocytes from children, and adult female and male subjects

Author(s) -

Alessandra Vottero,

Vincenzo Rochira,

Marzia Capelletti,

Isabella Viani,

Lucia Zirilli,

Tauro Maria Neri,

Cesare Carani,

Sergio Bernasconi,

Lucia Ghizzoni

Publication year - 2006

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.1.02102

Subject(s) - aromatase , luteal phase , medicine , endocrinology , follicular phase , testosterone (patch) , estrogen , menstrual cycle , aromatase inhibitor , messenger rna , biology , hormone , gene , cancer , breast cancer , biochemistry

Aromatase, the key enzyme involved in estrogen synthesis, is expressed in a variety of cells and tissues including human peripheral blood leukocytes (PBLs). The present study was designed to evaluate PBL aromatase gene expression in male and female subjects of different age groups. In addition, differences in gene expression during the follicular and luteal phase of the menstrual cycle in women, and before and after testosterone administration in men, were estimated.

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