Open AccessPro- and mature IGF-II during diet-induced weight loss in obese subjects
Author(s) -
Ulrick Espelund,
Jens Meldgaard Bruun,
Bjørn Richelsen,
Allan Flyvbjerg,
Jan Frystyk
Publication year - 2005
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.02028
Subject(s) - medicine , endocrinology , body mass index , obesity , weight loss , insulin , chemistry
In normal subjects up to 10% of circulating insulin-like growth factor II (IGF-II) consists of pro-IGF-II. However, its regulation and biological impact remains unknown. In obese subjects, serum free and total IGF-II are increased, and we therefore investigated the impact of obesity and diet on serum pro-IGF-II.
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