Open AccessThe HND mouse, a nonobese model of type 2 diabetes mellitus with impaired insulin secretion
Author(s) -
Fumihiko Horio,
Shin Teradaira,
Tsunehiko Imamura,
Rea Victoria P. Anunciado,
Misato Kobayashi,
Takao NAMIKAWA,
Ichiro Niki
Publication year - 2005
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.02023
Subject(s) - endocrinology , medicine , insulin , islet , diabetes mellitus , impaired glucose tolerance , biology , type 2 diabetes
This study aimed to develop a novel type 2 diabetes model designated the HND (Horio-Niki diabetic) mouse, by transferring diabetogenic genes from wild castaneus mice (Mus musculus castaneus) captured in the Philippines into laboratory mice (C57BL/6J:B6).
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