Glucagon inhibits ghrelin secretion in humans | Zendy

MA Arafat | Zendy; Bärbel Otto | Zendy; H. Rochlitz | Zendy; M. Tschöp | Zendy; Vivien Bahr | Zendy; Matthias Möhlig | Zendy; Sven Diederich | Zendy; Joachim Spranger | Zendy; A. Pfeiffer | Zendy

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Glucagon inhibits ghrelin secretion in humans

Author(s) -

MA Arafat,

Bärbel Otto,

H. Rochlitz,

M. Tschöp,

Vivien Bahr,

Matthias Möhlig,

Sven Diederich,

Joachim Spranger,

A. Pfeiffer

Publication year - 2005

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.1.01981

Subject(s) - medicine , endocrinology , ghrelin , glucagon , insulin , chemistry , hormone

It is well known that i.m. glucagon administration stimulates GH and cortisol release in humans, although the mechanisms are unclear. These effects are similar to those described for ghrelin on somatotroph and corticotroph function. The aim of the present study was to investigate the role of ghrelin in mediating the stimulatory effects of glucagon and to evaluate the effect of glucagon on ghrelin secretion.

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