Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women | Zendy

Stephanie C. E. Schuit | Zendy; Frank H. de Jong | Zendy; Lisette Stolk | Zendy; W. Nadia H. Koek | Zendy; Joyce B. J. van Meurs | Zendy; Mariette W.C.J. Schoofs | Zendy; M. Carola Zillikens | Zendy; Albert Hofman | Zendy; Johannes P.T.M. van Leeuwen | Zendy; Huibert A. P. Pols | Zendy; André G. Uitterlinden | Zendy

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Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women

Author(s) -

Stephanie C. E. Schuit,

Frank H. de Jong,

Lisette Stolk,

W. Nadia H. Koek,

Joyce B. J. van Meurs,

Mariette W.C.J. Schoofs,

M. Carola Zillikens,

Albert Hofman,

Johannes P.T.M. van Leeuwen,

Huibert A. P. Pols,

André G. Uitterlinden

Publication year - 2005

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.1.01973

Subject(s) - endocrinology , medicine , estrogen receptor alpha , estrone , haplotype , estrogen , testosterone (patch) , biology , allele , population , estrogen receptor , genotype , dehydroepiandrosterone sulfate , menopause , hormone , androgen , gene , genetics , breast cancer , cancer , environmental health

Postmenopausal estradiol (E(2)) levels vary widely between individuals and this variation is an important determinant of diseases such as osteoporosis. It has been suggested that the estrogen receptor alpha (ESR1) gene may influence peripheral E(2) levels, but the role of common sequence variations in the ESR1 gene is unclear.

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