Relationship between leptin, insulin, body composition and liver steatosis in non-diabetic moderate drinkers with normal transaminase levels
Author(s) -
Silvia Valtueña,
Filippo Numeroso,
Diego Ardigò,
Mario Pedrazzoni,
Laura Franzini,
Pier Marco Piatti,
Lucilla D. Monti,
Ivana Zavaroni
Publication year - 2005
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.01960
Subject(s) - medicine , endocrinology , steatosis , transaminase , leptin , insulin , diabetes mellitus , obesity , biology , enzyme , biochemistry
Obesity and insulin resistance play a major role in the development of liver steatosis (LS), but also relative leptin resistance has been reported to correlate with LS in humans. Our objective was to investigate the relationship between serum leptin, insulin, obesity and LS in non-diabetic males (n = 74) and postmenopausal females (n = 50) with normal transaminase levels and low-to-moderate alcohol intake.
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