The utility of three different methods for measuring urinary 18-hydroxycortisol in the differential diagnosis of suspected primary hyperaldosteronism | Zendy

Rebecca M. Reynolds | Zendy; Loai A. Shakerdi | Zendy; K Sandhu | Zendy; Euan M. Wallace | Zendy; P J Wood | Zendy; BR Walker | Zendy

Open Access

The utility of three different methods for measuring urinary 18-hydroxycortisol in the differential diagnosis of suspected primary hyperaldosteronism

Author(s) -

Rebecca M. Reynolds,

Loai A. Shakerdi,

K Sandhu,

Euan M. Wallace,

P J Wood,

BR Walker

Publication year - 2005

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.1.01922

Subject(s) - hyperaldosteronism , urine , adenoma , endocrinology , medicine , adrenal adenoma , urinary system , hyperplasia , differential diagnosis , urology , gastroenterology , chemistry , pathology , aldosterone

Urine 18-hydroxycortisol (18-OHF) measurements are claimed to discriminate between primary hyperaldosteronism due to Conn's syndrome/adrenal adenoma or idiopathic bilateral adrenal hyperplasia (BAH), and also to identify cases of glucocorticoid-suppressible hyperaldosteronism (GSH). We have evaluated three urine 18-OHF methods using a panel of urine samples from patients with hypertension.

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