Open AccessThe proatherogenic cytokine interleukin-18 is secreted by human adipocytes
Author(s) -
Thomas Skurk,
Hubert Kolb,
Sylvia Müller-Scholze,
K Röhrig,
Hans Hauner,
Christian Herder
Publication year - 2005
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.01897
Subject(s) - adipose tissue , medicine , endocrinology , adipogenesis , interleukin 6 , cytokine , immune system , interleukin , adipocyte , biology , immunology
Interleukin (IL)-18, an important mediator of innate immunity and strong risk factor for the development of cardiovascular disease, was shown recently to be elevated in obesity. The aim of our study was to investigate whether human adipocytes produce IL-18.
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