Ethinylestradiol and testosterone have divergent effects on circulating IGF system components in adolescents with constitutional tall stature
Author(s) -
Raoul Rooman,
L. Op De Beeck,
M. De Martin,
Jaap van Doorn,
Subburaman Mohan,
M. V. L. Du Caju
Publication year - 2005
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.01880
Subject(s) - medicine , endocrinology , testosterone (patch) , estrogen , ethinylestradiol , radioimmunoassay , androgen , insulin like growth factor , estrogen therapy , tall stature , growth factor , population , hormone , receptor , environmental health , research methodology
Pharmacological doses of estrogens or testosterone are used to limit the final height of girls or boys with constitutional tall stature but the mechanism behind this growth inhibition is still debated. We therefore studied the changes in the circulating components of the insulin-like growth factor (IGF) system during high dose sex steroid therapy.
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