Diagnosis of GH deficiency in the transition period: accuracy of insulin tolerance test and insulin-like growth factor-I measurement
Author(s) -
Mohamad Maghnie,
Gianluca Aimaretti,
Simonetta Bellone,
Gianni Bona,
J. Bellone,
Roberto Baldelli,
Carlo De Sanctis,
L Gargantini,
Roberto Gastaldi,
Lucia Ghizzoni,
Andrea Secco,
Carmine Tinelli,
Ezio Ghigo
Publication year - 2005
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.01873
Subject(s) - ighd , medicine , insulin tolerance test , endocrinology , growth hormone deficiency , hypoglycemia , insulin , reference range , cohort , hypopituitarism , growth hormone , hormone , insulin resistance , insulin sensitivity
A consensus exists that severe growth hormone deficiency (GHD) in adults is defined by a peak GH response to insulin-induced hypoglycemia (insulin tolerance test, ITT) of less than 3 microg/l based on a cohort of subjects with a mean age of 45 years.
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