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Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic β-cells
Author(s) -
Steen B. Haugaard,
Ove Andersen,
Flemming Dela,
Jens J. Holst,
Heidi Storgaard,
Mogens Fenger,
Johan Iversen,
Sten Madsbad
Publication year - 2005
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.1.01835
Subject(s) - lipodystrophy , endocrinology , medicine , lipid metabolism , carbohydrate metabolism , human immunodeficiency virus (hiv) , metabolism , virology , biology , antiretroviral therapy , viral load
Lipodystrophy and insulin resistance are prevalent among human immunodeficiency virus (HIV)-infected patients on combined antiretroviral therapy (HAART). Aiming to provide a detailed description of the metabolic adverse effects of HIV-lipodystrophy, we investigated several aspects of glucose metabolism, lipid metabolism and beta-cell function in lipodystrophic HIV-infected patients.

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