Thyroid and adrenal axis in major depression: a controlled study in outpatients | Zendy

J. Brouwer | Zendy; Bente C. Appelhof | Zendy; Witte J.G. Hoogendijk | Zendy; Jochanan Huyser | Zendy; Erik Endert | Zendy; Cassandra Zuketto | Zendy; Aart H. Schene | Zendy; Jan G.P. Tijssen | Zendy; Richard van Dyck | Zendy; Wilmar M. Wiersinga | Zendy; Eric Fliers | Zendy

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Thyroid and adrenal axis in major depression: a controlled study in outpatients

Author(s) -

J. Brouwer,

Bente C. Appelhof,

Witte J.G. Hoogendijk,

Jochanan Huyser,

Erik Endert,

Cassandra Zuketto,

Aart H. Schene,

Jan G.P. Tijssen,

Richard van Dyck,

Wilmar M. Wiersinga,

Eric Fliers

Publication year - 2005

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.1.01828

Subject(s) - endocrinology , medicine , hypothalamic–pituitary–thyroid axis , depression (economics) , thyroid , thyroid hormones , economics , macroeconomics

Major depressive disorder has been associated with changes in the hypothalamus-pituitary-thyroid (HPT) axis and with hypercortisolism. However, the changes reported have been at variance, probably related to in- or outpatient status, the use of antidepressant medication and the heterogeneity of depression. We therefore conducted a controlled study in unipolar depressed outpatients who had been free of antidepressants for at least 3 months.

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