Expression of betaglycan in pregnant tIssues throughout gestation
Author(s) -
Pasquapina Ciarmela,
Pasquale Florio,
Paolo Toti,
Daniel Grasso,
Rosa Santopietro,
P Tosi,
Felice Petraglia
Publication year - 2003
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1490433
Subject(s) - decidua , cytotrophoblast , trophoblast , placenta , syncytiotrophoblast , decidual cells , biology , fetal membrane , endocrinology , chorionic villi , medicine , fetus , amnion , andrology , pregnancy , stromal cell , gestation , genetics
Betaglycan is a membrane-anchored proteoglycan involved in mediating the passage of transforming growth factor-beta (TGF-beta), inhibin and activin activities into cells. TGF-beta and inhibin-related proteins are growth factors that are expressed by several tIssues and in pregnancy. They have a function in modulating the growth, differentiation and invasion of the placental trophoblast.
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