Acute plasma glucose increase, but not early insulin response, regulates plasma ghrelin | Zendy

L. Briatore | Zendy; G. Andraghetti | Zendy; Renzo Cordera | Zendy

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Acute plasma glucose increase, but not early insulin response, regulates plasma ghrelin

Author(s) -

L. Briatore,

G. Andraghetti,

Renzo Cordera

Publication year - 2003

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.0.1490403

Subject(s) - medicine , endocrinology , ghrelin , insulin , basal (medicine) , bolus (digestion) , plasma glucose , pancreatic hormone , insulin resistance , hormone

The independent role of glucose and insulin in ghrelin regulation is still controversial; this is also because in healthy subjects it is difficult to isolate the increase of glucose from that of insulin. The aim of this study was to discriminate the effect of glucose increase alone and early insulin response on plasma ghrelin, comparing ghrelin variation after i.v. glucose between healthy subjects and type 2 diabetic (T2DM) subjects, in whom the early insulin response to i.v. glucose is abolished.

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