Open AccessDown-regulation of proliferation and up-regulation of apoptosis by gonadotropin-releasing hormone agonist in cultured uterine leiomyoma cells
Author(s) -
Yin Wang,
Hidetoshi Matsuo,
O Kurachi,
Takeshi Maruo
Publication year - 2002
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1460447
Subject(s) - uterine leiomyoma , apoptosis , endocrinology , medicine , leiomyoma , agonist , proliferating cell nuclear antigen , cell growth , tunel assay , receptor , mtt assay , biology , chemistry , andrology , uterus , immunohistochemistry , pathology , genetics , biochemistry
To elucidate the direct effects of gonadotropin-releasing hormone agonist (GnRHa) on the growth of human uterine leiomyoma cells, cell proliferation and apoptosis in cultured leiomyoma cells treated with GnRHa were investigated.
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