Production of hyaluronan and chondroitin sulphate proteoglycans from human arterial smooth muscle--the effect of glucose, insulin, IGF-I or growth hormone
Author(s) -
Christian Erikstrup,
Lars Møller Pedersen,
Lene Heickendorff,
T. Ledet,
Lars Melholt Rasmussen
Publication year - 2001
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1450193
Subject(s) - medicine , endocrinology , insulin , trichloroacetic acid , proteoglycan , chemistry , hyaluronic acid , glycosaminoglycan , extracellular matrix , acromegaly , hormone , biology , biochemistry , growth hormone , genetics
Although it is recognized that the extracellular matrix is important for cell proliferation, migration and metabolism of growth factors, the regulation of the synthesis of hyaluronan and chondroitin sulphate proteoglycan (CSPG) in the vessel wall is poorly understood.
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