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Orexin-A and leptin change inversely in fasting non-obese subjects
Author(s) -
Gen Komaki,
Yu Matsumoto,
Nishikata Hiroaki,
Keisuke Kawai,
Tomoyoshi Nozaki,
Masahide Takii,
Hiroshi Sogawa,
Chiharu Kubo
Publication year - 2001
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1440645
Subject(s) - medicine , endocrinology , leptin , obesity , orexin , orexin a , neuropeptide , receptor
Leptin, neuropeptide-Y (NPY) and orexin are peptides regulating energy metabolism and appetite control. NPY and orexin are mainly found in the central nervous system and they have also recently been found in the peripheral nervous system. We investigated how fasting affects changes in circulating concentrations of these peptides and their association with nutritional and metabolic parameters in humans.

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