Open AccessGlucose stimulates and insulin inhibits release of pancreatic TRH in vitro
Author(s) -
Július Benický,
V. Štrbák
Publication year - 2000
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1420060
Subject(s) - medicine , endocrinology , insulin , glucagon , pancreatic islets , basal (medicine) , stimulation , pancreatic hormone , l glucose , chemistry , biology , islet , insulin resistance
Pancreatic TRH is present in insulin-producing B-cells of the islets of Langerhans. There is fragmentary evidence that it may be involved in glucoregulation. The aim of our present study was to analyze how glucose and insulin affect TRH secretion by the pancreatic islets.
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