Neurosurgery restores late GH rise after glucose-induced suppression in cured acromegalics | Zendy

Roberto Attanasio | Zendy; G. Oppizzi | Zendy; S. Lodrini | Zendy; D. Dallabonzana | Zendy; M Barausse | Zendy; Paola Orlandi | Zendy; N DaRe | Zendy; Renato Cozzi | Zendy

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Neurosurgery restores late GH rise after glucose-induced suppression in cured acromegalics

Author(s) -

Roberto Attanasio,

G. Oppizzi,

S. Lodrini,

D. Dallabonzana,

M Barausse,

Paola Orlandi,

N DaRe,

Renato Cozzi

Publication year - 1999

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje.0.1400023

Subject(s) - acromegaly , medicine , endocrinology , basal (medicine) , nadir , pituitary adenoma , transsphenoidal surgery , adenoma , neurosurgery , growth hormone , diabetes mellitus , surgery , hormone , satellite , aerospace engineering , engineering

A decrease of GH levels below 2 microg/l after an oral glucose tolerance test (OGTT) is still currently accepted as the gold standard for assessing cure in surgically treated acromegaly. Whether glucose-induced suppression of GH is accompanied by a restoration of normal GH late rebound has not yet been evaluated in this disease. In order to assess the restoration of normal GH regulation after removal of a pituitary adenoma, we have evaluated GH changes after an OGTT in a series of selected acromegalic patients (transsphenoidal surgery and lack of pituitary failure).

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