The diagnostic value of first-voided urinary LH compared with GNRH-stimulated gonadotropins in differentiating slowly progressive from rapidly progressive precocious puberty in girls
Author(s) -
Am Zung,
Ella Burundukov,
Mira Ulman,
Tamar Glaser,
Moshe Rosenberg,
Malka Chen,
Zvi Zadik
Publication year - 2014
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-14-0010
Subject(s) - medicine , bone age , endocrinology , precocious puberty , urinary system , hormone
Characterization of pubertal progression is required to prevent unnecessary intervention in unsustained or slowly progressive (SP) precocious puberty (PP), while delivering hormonal suppression in rapidly progressive (RP) PP. We aimed to assess the diagnostic value of first-voided urinary LH (ULH) compared with GNRH-stimulated gonadotropins in differentiating these forms of PP.
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