Diverse impacts of aging on insulin resistance in lean and obese women with polycystic ovary syndrome: evidence from 1345 women with the syndrome | Zendy

Sarantis Livadas | Zendy; Αναστάσιος Κόλλιας | Zendy; Dimitrios Panidis | Zendy; Evanthia DiamantiKandarakis | Zendy

Open Access

Diverse impacts of aging on insulin resistance in lean and obese women with polycystic ovary syndrome: evidence from 1345 women with the syndrome

Author(s) -

Sarantis Livadas,

Αναστάσιος Κόλλιας,

Dimitrios Panidis,

Evanthia DiamantiKandarakis

Publication year - 2014

Publication title -

european journal of endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 148

eISSN - 1479-683X

pISSN - 0804-4643

DOI - 10.1530/eje-13-1007

Subject(s) - polycystic ovary , insulin resistance , medicine , anovulation , overweight , hyperandrogenism , endocrinology , outpatient clinic , metabolic syndrome , free androgen index , cohort , body mass index , insulin , obesity

Polycystic ovary syndrome (PCOS) represents a moving spectrum of hormonal to metabolic abnormalities, as women with the syndrome are aging. Hormonal abnormalities, anovulation, and hyperandrogenic signs were predominant during the early years of PCOS and fade away with the years. Metabolic abnormalities and insulin resistance (IR) remain throughout the PCOS life cycle; however, it is unclear as to how they change, as women with the syndrome are aging.

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