Open AccessClinical, hormonal and molecular characterization of pituitary ACTH adenomas without (silent corticotroph adenomas) and with Cushing's disease
Author(s) -
Gérald Raverot,
Anne Wierinckx,
Emmanuel Jouanneau,
Carole Auger,
Françoise BorsonChazot,
Joël Lachuer,
Michel Pugeat,
Jacqueline Trouillas
Publication year - 2010
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-10-0076
Subject(s) - corticotropic cell , medicine , endocrinology , cushing's disease , proopiomelanocortin , adrenocorticotropic hormone , adenoma , hormone , biology , pituitary gland , disease
Silent corticotroph adenomas (SCAs) are rare pituitary tumours immunoreactive for ACTH, but without clinical evidence of Cushing's disease. We characterized SCAs based on clinical, hormonal and molecular data, and compared the characteristics of these tumours with those of macro (MCA)- and micro (mCA)-ACTH adenomas with Cushing's disease.
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