Serum osteoprotegerin concentrations are decreased in women with the polycystic ovary syndrome
Author(s) -
Héctor F. EscobarMorreale,
José I. BotellaCarretero,
M. Ángeles MartínezGarcía,
Manuel LuqueRamírez,
Francisco ÁlvarezBlasco,
José L. San Millán
Publication year - 2008
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-08-0107
Subject(s) - osteoprotegerin , medicine , endocrinology , polycystic ovary , rankl , body mass index , obesity , receptor , insulin resistance , activator (genetics)
Osteoprotegerin (OPG), an inhibitor of osteoclastic bone resorption, has a variety of functions including anti-inflammatory effects and a possible cardiovascular protective role. Both low-grade chronic inflammation and cardiovascular risk are increased in women with the polycystic ovary syndrome (PCOS). We aimed to study serum OPG concentrations in PCOS patients.
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