Open AccessImpact of total cumulative glucocorticoid dose on bone mineral density in patients with 21-hydroxylase deficiency.
Author(s) -
Zeina Chakhtoura,
Anne Bachelot,
Dinane SamaraBoustani,
Jean-Charles Ruiz,
Bruno Donadille,
Jérôme Dulon,
Sophie Christin-Maître,
Claire Bouvattier,
M C Raux-Demay,
Philippe Bouchard,
JeanClaude Carel,
Juliane Léger,
Frédérique Kuttenn,
Michel Polak,
Philippe Touraine
Publication year - 2008
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-07-0887
Subject(s) - medicine , glucocorticoid , bone mineral , femoral neck , endocrinology , congenital adrenal hyperplasia , demineralization , cumulative dose , bone density , osteoporosis , 21 hydroxylase , dentistry , enamel paint
It remains controversial whether long-term glucocorticoids are charged of bone demineralization in patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. The aim of this study was to know whether cumulative glucocorticoid dose from the diagnosis in childhood to adulthood in patients with CAH had a negative impact on bone mineral density (BMD).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom