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Increased basal and pulsatile secretion of FSH and LH in young men with 47,XXY or 46,XX karyotypes.
Author(s) -
Lise Aksglæde,
Rikke Beck Jensen,
Elisabeth Carlsen,
Petra Kok,
Daniel M. Keenan,
Johannes D. Veldhuis,
Niels E. Skakkebæk,
Anders Juul
Publication year - 2008
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-07-0709
Subject(s) - medicine , endocrinology , pulsatile flow , basal (medicine) , gonadotropin , secretion , biology , hormone , insulin
The regulation of normal sexual maturation and reproductive function is dependent on a precise hormonal regulation at hypothalamic, pituitary, and gonadal levels. The aim of this study was to investigate the neuroendocrine integrity of the pituitary-gonadal axis in patients with primary testicular failure due to supernumerary X chromosomes.

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