Open AccessRetinol-binding protein-4 is not strongly associated with insulin sensitivity in normal pregnancies.
Author(s) -
Thor Ueland,
T Dalsoren,
Nanna Voldner,
Kristin Godang,
Tore Henriksen,
Jens Bollerslev
Publication year - 2008
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-07-0682
Subject(s) - medicine , endocrinology , insulin resistance , retinol binding protein 4 , leptin , insulin , pregnancy , body mass index , obesity , glucose tolerance test , biology , adipokine , genetics
Recently, experimental and clinical studies suggest that retinol-binding protein-4 (RBP4) may provide a link between obesity and insulin resistance. However, no previous studies have investigated the impact of circulating RBP4 on measures of insulin resistance in normal pregnant women, and the objective of this study is to measure serum RBP4 in early and late pregnancy and relate these to measures of insulin resistance and secretion controlling for changes in fat mass.
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