Multidisciplinary Inquiry-Based Investigation Learning Using an Ex Ovo Chicken Culture Platform: Role of Vitamin A on Embryonic Morphogenesis | Zendy

Philip R. Buskohl | Zendy; Russell A. Gould | Zendy; Susan Curran | Zendy; Shivaun D. Archer | Zendy; Jonathan T. Butcher | Zendy

Open Access

Multidisciplinary Inquiry-Based Investigation Learning Using an Ex Ovo Chicken Culture Platform: Role of Vitamin A on Embryonic Morphogenesis

Author(s) -

Philip R. Buskohl,

Russell A. Gould,

Susan Curran,

Shivaun D. Archer,

Jonathan T. Butcher

Publication year - 2012

Publication title -

the american biology teacher

Language(s) - English

Resource type - Journals

eISSN - 1938-4211

pISSN - 0002-7685

DOI - 10.1525/abt.2012.74.9.7

Subject(s) - in ovo , retinoic acid , morphogenesis , biology , developmental biology , embryonic stem cell , microbiology and biotechnology , embryo , engineering ethics , physiology , genetics , cell culture , engineering , gene

Embryonic development offers a unique perspective on the function of many biological processes because of embryos’ heightened sensitivity to environmental factors. This hands-on lesson investigates the effects of elevated vitamin A on the morphogenesis of chicken embryos. The active form of vitamin A (retinoic acid) is applied to shell-less (ex ovo) cultured chick embryos, which are highly accessible and intrinsically spawn inquiry. The student activities mirror the scientific research process, including review of scientific literature, hypothesis formation, experimental design, interpretation of data, and re-evaluation of the initial hypothesis. This exercise supports instruction on developmental biology, biophysics, animal research, and experimental design and is motivated by a clinically relevant health issue.

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