Serum sialic acid and its lipid and protein bounds as possible biomarkers of acute myocardial infarction in Erbil city

Backgrounds and objectives: Myocardial infarction (MI) usually occurs when coronary blood flow decreases abruptly after a thrombotic occlusion of a coronary artery previously affected by atherosclerosis. Sialic acid (SA) is attached to non reducing residues of the carbohydrate chains of glycoproteins and glycolipids. An elevation in serum TSA , LBSA and PBSA concentrations has been observed in a number of pathological conditions .The aim of the study was to determine the serum TSA and its LBSA and PBSA in patients with acute myocardial infarction (AMI). Methods: Serum TSA , LBSA and PBSA concentrations were evaluated by UV/VIS spectrophotometry in (100) apparently healthy individuals and ( 100 ) newly diagnosed AMI patients . Results: The mean levels of serum TSA , LBSA and PBSA in AMI patients were significantly higher ( P < 0.05 ) than those of apparently healthy individuals . Conclusion: The results indicate that the serum values of TSA, LBSA and PBSA appeared to be of a value in diagnosis of AMI . Key wards: AMI , TSA , LBSA , PBSA