Antimicrobial Photodynamic Therapy: An Effective Alternative Approach to Control Bacterial Infections | Zendy

Hassan Mahmoudi | Zendy; Abbas Bahador | Zendy; Maryam Pourhajibagher | Zendy; Mohammad Yousef Alikhani | Zendy

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Antimicrobial Photodynamic Therapy: An Effective Alternative Approach to Control Bacterial Infections

Author(s) -

Hassan Mahmoudi,

Abbas Bahador,

Maryam Pourhajibagher,

Mohammad Yousef Alikhani

Publication year - 2018

Publication title -

journal of lasers in medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.443

H-Index - 21

eISSN - 2228-6721

pISSN - 2008-9783

DOI - 10.15171/jlms.2018.29

Subject(s) - photodynamic therapy , medicine , antimicrobial , photosensitizer , methylene blue , adjuvant therapy , microbiology and biotechnology , surgery , chemotherapy , photocatalysis , biochemistry , chemistry , organic chemistry , biology , catalysis

The purpose of this review was to evaluate the available literature for in vitro and in vivo effectiveness of antimicrobial Photodynamic therapy (aPDT) in the field of bacteriology. Methods: A review of the relevant articles carried out in PubMed and Scopus to determine the efficiency of aPDT used in the reduction of microbial infection. Thirty-one relevant documents retrieved from PubMed, Scopus by inserting "antimicrobial photodynamic therapy" and "bacterial infection" and "photodynamic therapy" keywords. Results: According to different results, aPDT can be used as an adjuvant for the treatment of infectious diseases. The use of photosensitizer methylene blue, toluidine blue O (TBO), indocyanine green with light diode laser centered at (630±10 nm) and (650±10 nm) wavelengths have been shown to have significant results for the treatment of infectious diseases and bactericidal properties Conclusion: These findings suggest that, aPDT can be an efficient method in the treatment of localized and superficial infections.

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