Effect of Surface Modification on Viability of L929 Cells on Zirconia Nanocomposite Substrat
Author(s) -
Moluk Aivazi,
Mohammadhossein Fathi,
Farahnaz Nejatidanesh,
Vajihesadat Mortazavi,
Batoul Hashemi Beni,
JP Matinlinna
Publication year - 2017
Publication title -
journal of lasers in medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.443
H-Index - 21
eISSN - 2228-6721
pISSN - 2008-9783
DOI - 10.15171/jlms.2018.18
Subject(s) - viability assay , medicine , nanocomposite , cubic zirconia , surface modification , yttrium , osseointegration , bioceramic , scanning electron microscope , laser , materials science , nuclear chemistry , composite material , biomedical engineering , chemical engineering , implant , surgery , cell , metallurgy , oxide , ceramic , chemistry , genetics , engineering , biology , physics , optics
Zirconia bioceramic can be considered for metallic replacement in dental implant applications. A proper method of surface modification may promote better osseointegration. Methods: In study evaluated viability of fibroblast cell following surface treatment. Therefore, viability L929 cells were characterized using MTT assay and scanning electron microscopy. Results: The viability assessment determined significant differences A-Y-TZP20 without surface treatment as compared to laser surface treatment (B), laser surface treatment + hydroxyapatiteyttrium stabilized tetragonal zirconia nanocomposite coat (C) and control. This study demonstrated that L929 cells approximately proliferated and spread on A-Y-TZP20 nanocomposite disk in laser surface treatment(B), Laser surface treatment + hydroxiapatite-yttrium stabilized tetragonal zirconia nanocomposite coat (C) groups similar to control group. Conclusion: Laser surface treatment showed positive effect on the viability of L929 cells.
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