Ibuprofen - a Safe Analgesic During Cardiac Surgery Recovery? A Randomized Controlled Trial | Zendy

Saddiq Mohammad Qazi | Zendy; Eske Jesper Sindby | Zendy; Martin Nørgaard | Zendy

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Ibuprofen - a Safe Analgesic During Cardiac Surgery Recovery? A Randomized Controlled Trial

Author(s) -

Saddiq Mohammad Qazi,

Eske Jesper Sindby,

Martin Nørgaard

Publication year - 2015

Publication title -

journal of cardiovascular and thoracic research

Language(s) - English

Resource type - Journals

eISSN - 2008-6830

pISSN - 2008-5117

DOI - 10.15171/jcvtr.2015.31

Subject(s) - medicine , ibuprofen , analgesic , anesthesia , oxycodone , regimen , myocardial infarction , randomized controlled trial , renal function , lansoprazole , surgery , creatinine , adverse effect , receptor , opioid , pharmacology , helicobacter pylori

Postoperative pain-management with non-steroid anti-inflammatory drugs has been controversial, due to related side-effects. We investigated whether there was a significant difference between an oxycodone-based pain-management regimen versus a slow-release ibuprofen based regimen, in a short term post-cardiac surgery setting. Particular attention was given to the rate of myocardial infarction, sternal healing, gastro-intestinal complications, renal failure and all-cause mortality.

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