Investigation of DNA-damage and Chromosomal Aberrations in Blood Cells under the Influence of New Silver-based Antiviral Complex | Zendy

Evgenii Plotnikov | Zendy; Vladimir Silnikov | Zendy; A. B. Gapeyev | Zendy; Vladimir Plotnikov | Zendy

Open Access

Investigation of DNA-damage and Chromosomal Aberrations in Blood Cells under the Influence of New Silver-based Antiviral Complex

Author(s) -

Evgenii Plotnikov,

Vladimir Silnikov,

A. B. Gapeyev,

Vladimir Plotnikov

Publication year - 2016

Publication title -

advanced pharmaceutical bulletin

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.773

H-Index - 35

eISSN - 2251-7308

pISSN - 2228-5881

DOI - 10.15171/apb.2016.011

Subject(s) - comet assay , dna damage , dna , somatic cell , bone marrow , genotoxicity , biology , drug , chemistry , toxicity , microbiology and biotechnology , genetics , pharmacology , immunology , gene , organic chemistry

The problem of infectious diseases and drug resistance is becoming increasingly important worldwide. Silver is extensively used as an anti-infective agent, but it has significant toxic side effects. In this regard, it is topical to develop new silver compounds with high biological activity and low toxicity. This work is aimed to study DNA damage and chromosomal aberrations in blood cells under the influence of new silver-based compound of general formula C6H19Ag2N4LiO6S2, with antiviral activity.

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