Open AccessInfluence of Machine-Derived Smoke Yields on Biomarker of Exposure (BOE) Levels in Cigarette Smokers*
Author(s) -
Gerhard Scherer
Publication year - 2015
Publication title -
beiträge zur tabakforschung international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.253
H-Index - 16
eISSN - 1612-9237
pISSN - 0173-783X
DOI - 10.1515/cttr-2015-0004
Subject(s) - smoke , tobacco smoke , chemistry , cigarette smoke , toxicant , environmental chemistry , nicotine , benzene , toxicology , environmental health , medicine , organic chemistry , toxicity , biology
Individual uptake of tobacco smoke constituents by smoking is highly variable in cigarette smokers and cannot be predicted by smoking behaviour variables and machine-derived smoke yields. It is well established that uptake of smoke constituents is best described by a series of bio-markers of exposure (BOEs) such as metabolites of nico-tine, tobacco-specific nitrosamines (TSNAs), polycyclic aromatic hydrocarbons (PAHs), aromatic amines, benzene, 1,3-butadiene, acrolein, hydrogen cyanide, 2,5-dimethyl-furan and other smoke constituents