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Expression of endothelial cell-specific adhesion molecules in lungs after cardiac arrest
Author(s) -
F. Chen,
Nobuyuki Kondo,
Makoto Sonobe,
T. Fujinaga,
Hiromi Wada,
Toru Bando
Publication year - 2008
Publication title -
interactive cardiovascular and thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 56
eISSN - 1569-9293
pISSN - 1569-9285
DOI - 10.1510/icvts.2007.166355
Subject(s) - medicine , cell adhesion molecule , messenger rna , lung , ischemia , endothelial stem cell , claudin , andrology , endothelium , cadherin , cell , pathology , immunology , microbiology and biotechnology , gene , biology , tight junction , in vitro , biochemistry
A method to compensate for donor shortages could be donation after cardiac death. In this study, we considered endothelial cell-specific molecules, claudin-5 and VE-cadherin, as possible biomarkers predicting lung injury against warm ischemia. We investigated how the expression of these molecules could change after cardiac arrest in a mouse lung, comparing other molecules presumably relating with ischemia.

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