Scheduling with sequence-dependent batch setup times: planning tests for a pharmaceutic industry | Zendy

Jorge Orestes Cerdeira | Zendy; Rosa Figueiredo | Zendy; António Pereira | Zendy; Cristina Requejo | Zendy

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Scheduling with sequence-dependent batch setup times: planning tests for a pharmaceutic industry

Author(s) -

Jorge Orestes Cerdeira,

Rosa Figueiredo,

António Pereira,

Cristina Requejo

Publication year - 2011

Publication title -

international journal of mathematical modelling and numerical optimisation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.195

H-Index - 12

eISSN - 2040-3615

pISSN - 2040-3607

DOI - 10.1504/ijmmno.2011.040792

Subject(s) - scheduling (production processes) , schedule , computer science , obligation , pharmaceutical industry , due date , operations research , quality (philosophy) , job shop scheduling , sequence (biology) , operations management , reliability engineering , engineering , pharmacology , genetics , operating system , philosophy , epistemology , medicine , biology , law , political science

In this work, we propose an approach for a real sequence-dependent batch setup times scheduling problem arising in a pharmaceutical company. A legal obligation for the pharmaceutical industry is to monitor the quality of their products during its life cycle. The development of new pharmaceutical products (medicines) leads to a high number of batches to be tested in order to accomplish with certain regulatory obligations regarding maintaining safeguards on quality and safety. The time lines are critical in this process. The problem is how to manage and schedule a number of tests, that require setups and obey to certain precedence relations, to avoid delays in the answers.

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