Metabolic state and value-based decision-making in acute and recovered female patients with anorexia nervosa | Zendy

Fabio Bernardoni | Zendy; Nadine Bernhardt | Zendy; Shakoor Pooseh | Zendy; Joseph A. King | Zendy; Daniel Geisler | Zendy; Franziska Ritschel | Zendy; Ilka Boehm | Zendy; Maria Seidel | Zendy; Veit Roessner | Zendy; Michael N. Smolka | Zendy; Stefan Ehrlich | Zendy

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Metabolic state and value-based decision-making in acute and recovered female patients with anorexia nervosa

Author(s) -

Fabio Bernardoni,

Nadine Bernhardt,

Shakoor Pooseh,

Joseph A. King,

Daniel Geisler,

Franziska Ritschel,

Ilka Boehm,

Maria Seidel,

Veit Roessner,

Michael N. Smolka,

Stefan Ehrlich

Publication year - 2020

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.190031

Subject(s) - anorexia nervosa , value (mathematics) , psychology , anorexia , medicine , psychotherapist , psychiatry , eating disorders , computer science , machine learning

Patients with anorexia nervosa forgo eating despite emaciation and severe health consequences. Such dysfunctional decision-making might be explained by an excessive level of self-control, alterations in homeostatic and hedonic regulation, or an interplay between these processes. We aimed to understand value-based decision-making in anorexia nervosa and its association with the gut hormone ghrelin. Besides its homeostatic function, ghrelin has been implicated in the hedonic regulation of appetite and reward via the modulation of phasic dopamine signalling.

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