5-HT1A receptor, 5-HT2A receptor and serotonin transporter binding in the human auditory cortex in depression | Zendy

Louisa J. Steinberg | Zendy; Mark D. Underwood | Zendy; Mihran J. Bakalian | Zendy; Suham Kassir | Zendy; J. John Mann | Zendy; Victoria Arango | Zendy

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5-HT_1A receptor, 5-HT_2A receptor and serotonin transporter binding in the human auditory cortex in depression

Author(s) -

Louisa J. Steinberg,

Mark D. Underwood,

Mihran J. Bakalian,

Suham Kassir,

J. John Mann,

Victoria Arango

Publication year - 2019

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.180190

Subject(s) - serotonergic , serotonin transporter , serotonin plasma membrane transport proteins , serotonin , temporal cortex , endocrinology , medicine , temporal lobe , 5 ht receptor , psychology , neuroscience , receptor , biology , epilepsy

Serotonergic system abnormalities are implicated in many psychiatric disorders, including major depression. The temporal lobe receives a high density of serotonergic afferent projections, and responses in the primary auditory cortex to sound are modulated by serotonergic tone. However, the associations between changes in serotonergic tone, disease state and changes in auditory cortical function remain to be clarified.

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