Altered white matter connectivity in young people exposed to childhood abuse: a tract-based spatial statistics (TBSS) and tractography study | Zendy

Lena Lim | Zendy; Heledd Hart | Zendy; Henrietta Howells | Zendy; Mitul A. Mehta | Zendy; Andrew Simmons | Zendy; Kah Mirza | Zendy; Katya Rubia | Zendy

Open Access

Altered white matter connectivity in young people exposed to childhood abuse: a tract-based spatial statistics (TBSS) and tractography study

Author(s) -

Lena Lim,

Heledd Hart,

Henrietta Howells,

Mitul A. Mehta,

Andrew Simmons,

Kah Mirza,

Katya Rubia

Publication year - 2019

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.170241

Subject(s) - fractional anisotropy , uncinate fasciculus , fasciculus , inferior longitudinal fasciculus , white matter , psychiatry , psychology , corpus callosum , superior longitudinal fasciculus , splenium , tractography , child abuse , medicine , clinical psychology , poison control , neuroscience , magnetic resonance imaging , injury prevention , environmental health , radiology

Childhood abuse is associated with structural brain abnormalities. Few studies have investigated white matter tract abnormalities in medication-naive, drug-free individuals who experienced childhood abuse. We examined the association between childhood abuse and abnormalities in white matter tracts in that population, controlling for psychiatric comorbidities.

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