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Age-related deficits in intracortical myelination in young adults with bipolar disorder type I
Author(s) -
Manpreet Sehmbi,
Christopher D. Rowley,
Luciano Minuzzi,
Flávio Kapczinski,
Jacek M. Kwiecień,
Nicholas A. Bock,
Benício N. Frey
Publication year - 2019
Publication title -
journal of psychiatry and neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.767
H-Index - 99
eISSN - 1488-2434
pISSN - 1180-4882
DOI - 10.1503/jpn.170220
Subject(s) - bipolar disorder , psychology , white matter , neuroscience , audiology , psychiatry , medicine , cognition , magnetic resonance imaging , radiology
Previous studies have implicated white-matter-related changes in the pathophysiology of bipolar disorder. However, most of what is known is derived from in vivo subcortical white-matter imaging or postmortem studies. In this study, we investigated whole-brain intracortical myelin (ICM) content in people with bipolar disorder type I and controls.

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