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Four psychoradiological patterns of altered small-world properties are proposed. The analysis of altered small-world properties may provide novel insights into the pathophysiological mechanisms underlying psychiatric disorders from a connectomic perspective. In future connectome studies, the global network measures of both segregation and integration should be calculated to fully evaluate altered small-world properties in patients with a particular disease.

Psychoradiological patterns of small-world properties and a systematic review of connectome studies of patients with 6 major psychiatric disorders