Decreased serum pyridoxal levels in schizophrenia: meta-analysis and Mendelian randomization analysis | Zendy

Yukiko Tomioka | Zendy; Shusuke Numata | Zendy; Makoto Kinoshita | Zendy; Hidehiro Umehara | Zendy; Shin-ya Watanabe | Zendy; Masahito Nakataki | Zendy; Yoshimi Iwayama | Zendy; Tomoko Toyota | Zendy; Masashi Ikeda | Zendy; Hidenaga Yamamori | Zendy; Shinji Shimodera | Zendy; Atsushi Tajima | Zendy; Ryota Hashimoto | Zendy; Nakao Iwata | Zendy; Takeo Yoshikawa | Zendy; Tetsuro Ohmori | Zendy

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Decreased serum pyridoxal levels in schizophrenia: meta-analysis and Mendelian randomization analysis

Author(s) -

Yukiko Tomioka,

Shusuke Numata,

Makoto Kinoshita,

Hidehiro Umehara,

Shin-ya Watanabe,

Masahito Nakataki,

Yoshimi Iwayama,

Tomoko Toyota,

Masashi Ikeda,

Hidenaga Yamamori,

Shinji Shimodera,

Atsushi Tajima,

Ryota Hashimoto,

Nakao Iwata,

Takeo Yoshikawa,

Tetsuro Ohmori

Publication year - 2018

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.170053

Subject(s) - mendelian randomization , schizophrenia (object oriented programming) , odds ratio , medicine , pyridoxal , meta analysis , confidence interval , population , cohort study , psychiatry , endocrinology , gastroenterology , genotype , biology , genetics , biochemistry , gene , environmental health , phosphate , genetic variants

We found decreased serum pyridoxal levels in patients with schizophrenia in this observational study. However, we failed to obtain data supporting a causal relationship between pyridoxal levels and schizophrenia risk using the MR approach.

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